2009•Journal of clinical and experimental medicineRequires access

Expression of KAI1/CD82 in cervical squamous cell carcinoma tissue and its clinical significance

Shu Xiao

Abstract

Objective To investigate the clinical significance in KAI1/CD82 expressions in cervical squamous cancer tissues and normal cervical tissues.Methods The expression of KAI1/CD82 were assayed by SABC immunohistochemical methods in 54 cases of cervidal cancer tissues and 13 cases of normal cervical tissues.Results Positive expression of KAI1/CD82 was detected in 13 normal cervical tissue(13/13).KAI1/CD82 expression is down-regulated in cervical carcinoma(28/54,P0.01).The expression of KAI1/CD82 in cervical cancer tissues significantly correlate with lymph node metastasis(P0.01).Conclusion KAI1/CD82expression is down-regulated in cervical carcinoma,and is to correlate with lymph node metastasis.

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Key concepts: Medicine, Immunohistochemistry, Cervical cancer, Pathology, Clinical significance, Lymph node metastasis, Lymph node, Cervical carcinoma