A Brief Analysis of Encyclopedia of DNA Elements

In September,2012,more than 30 papers published on Nature,Genome Research,and Genome Biology,the ENCODE(Encyclopedia of DNA Elements) project achieved its first success.After the HGP(Human Genome Project) came to an end with a map of human genome sequence in 2001,we didn't know clearly how/where genes regulated by other factors.So,in September 2003,National Human Genome Research Institute launched a public research consortium named ENCODE,the Encyclopedia of DNA Elements,to identify all functional elements in the human genome sequence.Researchers pinpointed hundreds of thousands of landing spots for proteins that influence gene activity,many thousands of stretches of DNA that code for different types of RNA,and lots of places where chemical modifications serve to silence stretches of our chromosomes,concluding that 80% of the genome was biochemically active.Here,we review correlative information of about ENCODE and give readers instructions to recognize and apply achievements of ENCODE for human health service.