Evaluation of lisinopril's effect on early diabetic nephropathy patients with normal blood pressure in urinary protein

Objective To investigate the effect and the safety of lisinopril for controlling the urinary protein in early diabetic nephropathy patients.Methods Ninety-four early diabetic nephropathy patients with normal blood pressure were divided into two groups after their blood sugar were controlled into stability.And the data has no significant difference between the two groups.Group A(47 cases) took lisinopril,10 mg/d;While group B(47 cases) took Baoshenkang tablets.The quantity of urinary protein,the average artery pressure,the function of liver and kidney,the blood sugar,the blood fat and electrolyte were determined after treatment of 0,3,12,24 months. Results The urinary protein's quantity of group A after the treatment of 3 months had a significant difference with the condition before the treatment and the urinary protein's quantity of group B(P0.05).Conclusion Lisinopri is a safe medicine,which can reduce the quantity of urinary protein of early diabetic nephropathy patients with normal blood pressure.