2008•Chinese Journal of Modern Drug ApplicationRequires access

Study on content determination of Baicalin from extract powder of Scutellaria baicalensis Georgi by different extraction technique

Liao Xiao

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Abstract

Objective To establish a method for content determination of baicalin in extract powder of Scutellaria baicalensis Georgi and to optimize the extraction technique.Methods Taking Baicalin as index,we use the technique of HPLC to determine its content.Then compare the difference among water-extracting and acid-depositing;alcohol-extracting and acid-depositing and ultrasonic-method.Results The content from ultrasonic extraction of the baicalin is the highest.In the range of 7.58-121.36 μg,the baicalin shows good linear relationship.The recovery of baicalin is 99.25 %.Conclusion The ultrasonic extraction method is steady,reasonable,feasible and efficient.

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What this paper is about

Objective To establish a method for content determination of baicalin in extract powder of Scutellaria baicalensis Georgi and to optimize the extraction technique.Methods Taking Baicalin as index,we use the technique of HPLC to determine its content.Then compare the difference among water-extracting and acid-depositing;alcohol-extracting and acid-depositing and ultrasonic-method.Results The content from ultrasonic extraction of the baicalin is the highest.In the range of 7.58-121.36 μg,the baicalin shows good linear relationship.The recovery of baicalin is 99.25 %.Conclusion The ultrasonic extraction method is steady,reasonable,feasible and efficient.

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Available abstract

Objective To establish a method for content determination of baicalin in extract powder of Scutellaria baicalensis Georgi and to optimize the extraction technique.Methods Taking Baicalin as index,we use the technique of HPLC to determine its content.Then compare the difference among water-extracting and acid-depositing;alcohol-extracting and acid-depositing and ultrasonic-method.Results The content from ultrasonic extraction of the baicalin is the highest.In the range of 7.58-121.36 μg,the baicalin shows good linear relationship.The recovery of baicalin is 99.25 %.Conclusion The ultrasonic extraction method is steady,reasonable,feasible and efficient.

Key concepts: Baicalin, Scutellaria baicalensis, Extraction (chemistry), Chromatography, Chemistry, Content determination, Scutellaria, Ultrasonic sensor

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