2015Chinese Journal of Bone and Joint InjuryRequires access

Clinical analysis of efficacy of antibiotic bone cement in treatment of traumatic tibial osteomyelitis

Xiaoyu Zhang

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Abstract

Objective To discuss the effectiveness of antibiotic-impregnated cement for traumatic tibial osteomyelitis.Methods Between July 2008 and January 2013,23 patients with traumatic tibial osteomyelitis were treated. All patients were first treated by extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, closed woods by using primary closure or VSD technology according the wounds. After 7-10 days later, the wounds were debrided again, replaced with antibiotic bone cement chain beads and VSD depending on the circumstances, or skin graft, or tissue flap and plate fixation, or bone graft. Results After treatment, the infection was controlled, graft survived, skin elasticity was good without recurrence. Five cases received primary suture, and 4 cases were healed in first intention, while skin edge necrosis occurred in 1 case, and was controlled by wound healing and Kangfuxin. Thirteen cases underwent skin flap transplantation, 5cases stamps skin graft, all wound healed well, the average healing time was 31.6(14-167) days. All cases were followed up for 18 to 60 months(mean, 28.6 months), fracture had bone union, the average healing time was 9.2 months. Conclusion It has a good clinical result in the clinical treatment of traumatic osteomyelitis by taking an extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, full use of VSD, using flap or skin graft to close woods, combining with the use of systemic sensitive antibiotics.

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Objective To discuss the effectiveness of antibiotic-impregnated cement for traumatic tibial osteomyelitis.Methods Between July 2008 and January 2013,23 patients with traumatic tibial osteomyelitis were treated. All patients were first treated by extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, closed woods by using primary closure or VSD technology according the wounds. After 7-10 days later, the wounds were debrided again, replaced with antibiotic bone cement chain beads and VSD depending on the circumstances, or skin graft, or tissue flap and plate fixation, or bone graft. Results After treatment, the infection was controlled, graft survived, skin elasticity was good without recurrence. Five cases received primary suture, and 4 cases were healed in first intention, while skin edge necrosis occurred in 1 case, and was controlled by wound healing and Kangfuxin. Thirteen cases underwent skin flap transplantation, 5cases stamps skin graft, all wound healed well, the average healing time was 31.6(14-167) days. All cases were followed up for 18 to 60 months(mean, 28.6 months), fracture had bone union, the average healing time was 9.2 months. Conclusion It has a good clinical result in the clinical treatment of traumatic osteomyelitis by taking an extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, full use of VSD, using flap or skin graft to close woods, combining with the use of systemic sensitive antibiotics.

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Available abstract

Objective To discuss the effectiveness of antibiotic-impregnated cement for traumatic tibial osteomyelitis.Methods Between July 2008 and January 2013,23 patients with traumatic tibial osteomyelitis were treated. All patients were first treated by extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, closed woods by using primary closure or VSD technology according the wounds. After 7-10 days later, the wounds were debrided again, replaced with antibiotic bone cement chain beads and VSD depending on the circumstances, or skin graft, or tissue flap and plate fixation, or bone graft. Results After treatment, the infection was controlled, graft survived, skin elasticity was good without recurrence. Five cases received primary suture, and 4 cases were healed in first intention, while skin edge necrosis occurred in 1 case, and was controlled by wound healing and Kangfuxin. Thirteen cases underwent skin flap transplantation, 5cases stamps skin graft, all wound healed well, the average healing time was 31.6(14-167) days. All cases were followed up for 18 to 60 months(mean, 28.6 months), fracture had bone union, the average healing time was 9.2 months. Conclusion It has a good clinical result in the clinical treatment of traumatic osteomyelitis by taking an extensive debridement and focus clearance, antibiotic bone cement chain bead placed in the lesion area, full use of VSD, using flap or skin graft to close woods, combining with the use of systemic sensitive antibiotics.

Key concepts: Medicine, Surgery, Osteomyelitis, Debridement (dental), Bone healing, Bone cement, Antibiotics, Osteitis

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