Prognostic significance of the number of lymph nodes removed surgically in patients with colorectal cancer

Objective To assess the relationship between the number of recovered lymph nodes from specimens of patients with colorectal carcinoma and their prognosis. MethodsKG1 From 1989.1 to 2000.12,76 colorectal carcinoma patients undergoing radical resection were divided into two groups according to with or without lymph node metastasis. Each group were further substratified into two subgroups basing on the number of harvested lymph nodes or ≤50 in each patient. 5-year survival curves were estimated with the Kaplan-Meier method and compared by the log-rank test. ResultsWT5”BZ Analysis revealed that among node-negative patients, the 5-yerar's survival rate was 23% higher in patients with more than 50 nodes removed than those with less than 50. For node-positive patients, the difference of 5-year′s survival rate between the related two subgroups reached 36%.WT5”HZConclusion The number of lymph node resected has great impact on the long term survival of patients with colorectal cancer.