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Effects of lipofuscin in morbility of age-related macular degeneration

Hai Liu

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Abstract

Age-related macular degeneration (AMD) has been one of the most important causes of irreversible blindness in old individuals nowadays.Its incidence increases year by year.Due to the uncertainty of its pathogenesis,the effective treatment for AMD is unavailable.Recently researchers have indicated lipofuscin deposites below retina along with age,and through the effect of photochemistry,the functions of retinal pigment epithelium become abnormal,Photoreceptors' degeneration is increased and neovascularization in choroid form resulting in the occurrence of AMD.

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What this paper is about

Age-related macular degeneration (AMD) has been one of the most important causes of irreversible blindness in old individuals nowadays.Its incidence increases year by year.Due to the uncertainty of its pathogenesis,the effective treatment for AMD is unavailable.Recently researchers have indicated lipofuscin deposites below retina along with age,and through the effect of photochemistry,the functions of retinal pigment epithelium become abnormal,Photoreceptors' degeneration is increased and neovascularization in choroid form resulting in the occurrence of AMD.

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Available abstract

Age-related macular degeneration (AMD) has been one of the most important causes of irreversible blindness in old individuals nowadays.Its incidence increases year by year.Due to the uncertainty of its pathogenesis,the effective treatment for AMD is unavailable.Recently researchers have indicated lipofuscin deposites below retina along with age,and through the effect of photochemistry,the functions of retinal pigment epithelium become abnormal,Photoreceptors' degeneration is increased and neovascularization in choroid form resulting in the occurrence of AMD.

Key concepts: Macular degeneration, Lipofuscin, Retinal pigment epithelium, Degeneration (medical), Choroid, Retina, Choroidal neovascularization, Ophthalmology

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Effects of lipofuscin in morbility of age-related macular degeneration — Research Paper | ScholarLens