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Risk factors for pancreatic fistula after pancreatoduodenectomy

Hou Bao-hu

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Abstract

Objective To investigate the risk factors for pancreatic fistula after pancreatoduodenectomy (PD). Methods Data of patients received PD in our hospital in the recent 6 years was analyzed. Risk factors for pancreatic fistula after PD were analyzed. Additionally, the independent risk factors were screened and included in a multivariate Logistic regression for analysis. Results A total of 202 cases were included in this analysis , among whom 26 cases had postoperative pancreatic fistula (12.87%). There were significant differences on terms of age, BMI, ASA score, pancreatic duct diameter and soft pancreas between the two groups (P0.05). A further multivariate Logistic regression revealed that the pancreatic duct diameter smaller than 3 mm and soft pancreas could be treated as the independent risk factors for postoperative pancreatic fistula (pancreas texture OR=4.90, 95%CI: 1.12~18.91,P=0.02; pancreatic duct diameter OR = 3.76, 95% CI:1.51 ~ 12.41,P=0.03). Conclusion Pancreatic duct diameter smaller than 3 mm and soft pancreas were the independent risk factors for postoperative pancreatic fistula after PD.

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Objective To investigate the risk factors for pancreatic fistula after pancreatoduodenectomy (PD). Methods Data of patients received PD in our hospital in the recent 6 years was analyzed. Risk factors for pancreatic fistula after PD were analyzed. Additionally, the independent risk factors were screened and included in a multivariate Logistic regression for analysis. Results A total of 202 cases were included in this analysis , among whom 26 cases had postoperative pancreatic fistula (12.87%). There were significant differences on terms of age, BMI, ASA score, pancreatic duct diameter and soft pancreas between the two groups (P0.05). A further multivariate Logistic regression revealed that the pancreatic duct diameter smaller than 3 mm and soft pancreas could be treated as the independent risk factors for postoperative pancreatic fistula (pancreas texture OR=4.90, 95%CI: 1.12~18.91,P=0.02; pancreatic duct diameter OR = 3.76, 95% CI:1.51 ~ 12.41,P=0.03). Conclusion Pancreatic duct diameter smaller than 3 mm and soft pancreas were the independent risk factors for postoperative pancreatic fistula after PD.

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Available abstract

Objective To investigate the risk factors for pancreatic fistula after pancreatoduodenectomy (PD). Methods Data of patients received PD in our hospital in the recent 6 years was analyzed. Risk factors for pancreatic fistula after PD were analyzed. Additionally, the independent risk factors were screened and included in a multivariate Logistic regression for analysis. Results A total of 202 cases were included in this analysis , among whom 26 cases had postoperative pancreatic fistula (12.87%). There were significant differences on terms of age, BMI, ASA score, pancreatic duct diameter and soft pancreas between the two groups (P0.05). A further multivariate Logistic regression revealed that the pancreatic duct diameter smaller than 3 mm and soft pancreas could be treated as the independent risk factors for postoperative pancreatic fistula (pancreas texture OR=4.90, 95%CI: 1.12~18.91,P=0.02; pancreatic duct diameter OR = 3.76, 95% CI:1.51 ~ 12.41,P=0.03). Conclusion Pancreatic duct diameter smaller than 3 mm and soft pancreas were the independent risk factors for postoperative pancreatic fistula after PD.

Key concepts: Pancreatic fistula, Medicine, Pancreatic duct, Pancreas, Logistic regression, Gastroenterology, Fistula, Internal medicine

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