2007•Chinese Journal of Veterinary DrugRequires access
Antibacterial Susceptibility Test of Three Clinical Isolates and the Determination of Extended-spectrum Beta-lactamases
Long Ning-ke
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Abstract
In this experiment,we tested the antibacterial activity of beta-lactam antibiotics and combination with inhibitors against the pathogenic bacterium from chickens by twofold dilution method.And,the extended-spectrum beta-lactamase is also detected.The result shows that the three pathogenic bacterium isolates are not sensitive to beta-lactam,normal-used antibiotics and fluoroquinolones,some even resist them.But if cefalexin/sulbactam(2∶1),amoxicillin/clavulanic acid(4∶1),ceftriaxone/TB(4∶1),cefoperazone/TB(4∶1) are used in combination,the sensitivity of bacteria to beta-Lactam is recovered;!only one of the three pathogenic bacteria was found extended-spectrum beta-lactamase.