Separation of 2-picoline/2-ethanolpyridine by batch vacuum distillation

2-Picoline and heat-sensitive material 2-ethanolpyridine were separated by batch vacuum distillation.The effects of feed composition and operating pressure on vacuum distillation process were also investigated.The results showed that high vacuum in the column lowering the bottom temperature ensured the feed in the reboiler against the thermal degeneration.The optimal pressure was below 4325 Pa for 2-ethanolpyridine in vacuum distillation process.The mass fraction of 2-ethanolpyridine in the reboiler could be more than 97% and the yield of 2-ethanolpyridine could be over 86% under this condition.When the pressure was 1325 Pa the mass fraction of 2-picoline in the distillate and 2-ethanolpyridine in the reboiler were both up to 98%,with yields above 85%,meeting the requirements of industrial production well.