Clinical observation of painful ophthalmoplegia

Objective To improve diagnoses and treatment of painful ophthalmoplegia syndrome and study possible etiology of the syndrome.Methods Eighteen cases with painful ophthalmoplegia syndrome diagnosed clinically were collected and their modes of onset,the involvement of the cranial nerves and the results of the special examinations were analyzed.Results The syndrome of multiple cranial nerves with ophthalmopathy were found.Cerebrospinal fluid and neuroimaging examinations may be abnormal.Conclusion The patients with headache or sigle ophthalmoplegia must be diagnosed with exclusion.Possible etiology of the syndrome is nonspecific inflammatory with immune reaction,besides,satisfactory effect of adrenocorticotrophic hormone is acquired after corticosteroid treatment has no effect.