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2004•Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhiRequires access

Clinical signifinace of telomerease activity in human ovarian serous tumor

Jian Huang

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Abstract

Objective:To find out the clinical signficance of telomerease activity in diagnosis and differential diagnosis of ovarian serous tumor.Methods:In situ hybridization was used to detect telomerease TERT protein expression in 40 cases of ovarian serous tumor tissues (benign tissue from 20 cases, borderline tissue from 5 cases and malignant tissue from 15 cases).Results:Telomerease activity was detected in 5% of benign tissue (1 case), 60% of borderline tissues (3 cases) and 93.3% of malignant tissue (14 cases).Conclusions:Telomerease TERT protein expression may do help to diagnosis and differential diagnosis of ovarian serous tumor.

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Objective:To find out the clinical signficance of telomerease activity in diagnosis and differential diagnosis of ovarian serous tumor.Methods:In situ hybridization was used to detect telomerease TERT protein expression in 40 cases of ovarian serous tumor tissues (benign tissue from 20 cases, borderline tissue from 5 cases and malignant tissue from 15 cases).Results:Telomerease activity was detected in 5% of benign tissue (1 case), 60% of borderline tissues (3 cases) and 93.3% of malignant tissue (14 cases).Conclusions:Telomerease TERT protein expression may do help to diagnosis and differential diagnosis of ovarian serous tumor.

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Available abstract

Objective:To find out the clinical signficance of telomerease activity in diagnosis and differential diagnosis of ovarian serous tumor.Methods:In situ hybridization was used to detect telomerease TERT protein expression in 40 cases of ovarian serous tumor tissues (benign tissue from 20 cases, borderline tissue from 5 cases and malignant tissue from 15 cases).Results:Telomerease activity was detected in 5% of benign tissue (1 case), 60% of borderline tissues (3 cases) and 93.3% of malignant tissue (14 cases).Conclusions:Telomerease TERT protein expression may do help to diagnosis and differential diagnosis of ovarian serous tumor.

Key concepts: Serous fluid, Ovarian tumor, Differential diagnosis, Ovarian tissue, Pathology, Medicine, Ovary, Ovarian cancer

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