Clinic research on low dose atropine in treating severe organophosphorus pesticide poisoning

Objective:To estimate the clinic effect of the low dose atropine in treating organophosphorus pesticide poisoning.Methods:46 cases severe organophosphorus pesticide poisoning were treated on low dose atropine,compared with 42 cases which was treated on traditional way.Results:①46 cases in observation group were all cured.The total dosage given atropine was minmal 5 mg,maximal 46 mg,average(10.26±2.28) mg.While in control group,five were dead and death rate was 11.9%,observation group cure rate was higher than the control group(P0.05).②The observation group had no atropine poisoning,no rebound occurred and no intermediate syndromes(IMS).While in control group,18(42.9%) atropine poisoning,4 cases(9.52%) rebounds,4 cases(9.52%) IMS.Great differences revealed(P0.05).Conclusion:Low dose atropine is effective to treat severe organophosphorus pesticide poisoning and low rate of complication.