Experimental Studies on Anti-inflammation,Analgesic Action for Ronggensheng Capsule

Objective:Observing the influence of Ronggensheng Capsule on anti-inflammation,analgesic action and detumescence in the adjuvant-induced arthritis rat.Methods:Rat adjuvant arthritis model was established by Freund's complete adjuvant to observe the joint inflammation and swelling;and hot plate and writhing method to observe the Ronggensheng Capsule's analgesic effect in rat.Results: Ronggensheng Capsule could inhibit the rat secondary ankle swelling of arthritis,reduce inflammation index;extend the latent period of licking hind foot in the hot-plate test in mice and significantly reduce the acetic acid-induced writhing number in mice(P0.05 or P0.01).Experiments confirmed that high-dose group and meloxicam had no significant difference.Conclusion:Ronggensheng Capsule has a good anti-inflammatory and analgesic effect on swelling.