The distribution and drug resistance of pathogenic bacteria in urinary system infection

Objective To investigate the distribution and drug resistance of pathogenic bacteria in urinary system infection,and to provide reliable evidence for diagnosis and treatment of urinary system infectious disease and guide the rational administration of antibiotics.Methods The clinical data of urine culture samples from the inpatients and outpatients during the last two years was retrospectively analyzed,including bacterial identification and drug resistance of 382 clinical isolates.Results The gram negative bacilli were predominant bacteria,and their detection rate exceeded 70.0%,in which Escherichia coli accounted for 50.3%,followed by Enterococci(13.7%).Moreover,the detection of Enterococci displayed a elevating trend.The drug resistance rate of E.coli to imipenem was the lowest(2.6%),but higher to most beta-lactam antibiotics(35.0%).The Enterococci were resistant to common antibiotics(drug resistance rate:38.0%-90%),but sensitive to vancomycin with a low resistance rate(3.8%).Conclusion The main pathogens are Enterobacteriaceae in urinary system infection.The pathogenic bacteria were highly resistant to cephalosporins and quinolones.Antibiotics should be used rationally according to drug susceptibility test results so as to diminish the spread of drug resistance.