2014•Evidence-Based PracticeRequires access

Is a single dose of oral ondansetron effective in reducing rates of intravenous rehydration in children with gastroenteritis?

Yael Smiley, David V. Power

Abstract

Evidence-Based Answer One dose of oral ondansetron given in the emergency department significantly reduces the number of episodes of vomiting during oral rehydration therapy in children with acute gastroenteritis and reduces the number of children who require IV rehydration (SOR: A, meta-analysis).

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Available abstract

Key concepts: Ondansetron, Medicine, Acute gastroenteritis, Vomiting, Oral rehydration therapy, Anesthesia, Intravenous fluid, Emergency department