Application of SPECT/CT Fusion Imaging in ~(99)Tc~m-MIBI Thyroid Scintigraphy

Objective To explore the clinical value of SPECT-CT fusion imaging in 99Tcm-methoxy isobutyl isonitrile(MIBI) thyroid scintigraphy. Methods 103 patients with nonfunctional thyroid nodules were examined by using dual-phase 99Tcm-MIBI thyroid scintigraphy(15min and 2h) and then examined by using SPECT-CT fusion imaging. The results of 103 patients achieved through dualphase 99Tcm-MIBI thyroid scintigraphy and SPECT-CT fusion imaging were compared with those of pathological examination. Results The sensitivity, specifi city and accuracy of dual-phase 99Tcm-MIBI thyroid scintigraphy in diagnosing benign and malignant of nonfunctional thyroid nodules were 59.1%, 49.4% and 51.4%, respectively while those of SPECT-CT fusion imaging were 81.8%, 76.5% and 77.7%, respectively. Conclusion The diagnosis accuracy of 99Tcm-MIBI thyroid scintigraphy in nonfunctional thyroid nodules can be improved with the application of SPECT-CT fusion imaging, who can provide reliable information for clinical diagnosis.