ScholarLens Back to search
2006•The Journal of Pharmaceutical PracticeRequires access

Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats

Ting Han

Open publisher page 0 citations

Abstract

Objective: To study the effects of Qingzhiyuan soft capsule(QZY) on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods: Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels. They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets. After three weeks, blood lipid and antioxidant activity were determined respectively. Results: Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P 0. 05). Conclusion: QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.

About this research paper

What this paper is about

Objective: To study the effects of Qingzhiyuan soft capsule(QZY) on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods: Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels. They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets. After three weeks, blood lipid and antioxidant activity were determined respectively. Results: Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P 0. 05). Conclusion: QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To study the effects of Qingzhiyuan soft capsule(QZY) on blood lipid and antioxidant activity in hyperlipi-demia rats. Methods: Fifty Wister rats were randomly divided into five groups according to body weight and serum cholesterol levels. They were fed one of five diets, a reference diet, a high fat supplemented diet and a high fat supplemented with 20mg/kg, 5mg/kg QZY, a positive diets. After three weeks, blood lipid and antioxidant activity were determined respectively. Results: Compared with model, QZY could reduced the serum TC, TG, LDL-C concentration, increased SOD and GSH-Px activities, decreased MDA level significantly(P 0. 05). Conclusion: QZY might play an important role in preventing hyperlipidemia through its antioxidative effect.

Key concepts: Hyperlipidemia, Capsule, Antioxidant, Blood lipids, Total cholesterol, Chemistry, Endocrinology, Internal medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effects of Qingzhiyuan soft capsule on blood lipid and antioxidantion in hyperlip-idemia rats — Research Paper | ScholarLens