The clinical application of DTI and DTT on acute cerebral infarction

Objective To investigate the characteristics of magnetic resonance diffusion tensor imaging(DTI) and the relationship between infracted and cortical spinal tract(CST) in patients with acute cerebral infarction in order to assess prognosis. Methods Conventional magnetic resonance imaging(MRI) and diffusion weighted imaging (DWI)、DTI/ diffusion tensor tractography(DTT) were performed on 45 patients with acute cerebral infarction. The decreasing percentage of fractional anistrophy(FA) value in infarcted were computed. Displacement, continuity and injured condition of CST were observed. At the same time, the patients were measured NIHSS. Results ①The decreasing percentage of FA value in infarcted has significant positive correlation with NIHSS1(r=0.411,P0.01).②There were 15 cases whose CST were complete,20 cases whose CST were complete but compression shift,10 cases whose CST were break. The injured degree of CST has significant positive correlation with NIHSS2(r=0.894,P0.01).Conclusion The larger the decreasing percentage of FA is, the more serious the clinical manifestation is. The patients with injured CST would have more serious damage of the neuromotor function and worse functional rehabilitation.