Identification and quantitative determination of berberine hydrochloride of Niaoyanqing tablet
Long Jie-chao
Abstract
Long Jie-chao
Abstract
OBJECTIVE To identify and determine of berberine hydrochloride of Niaoyanqing tablet.METHODS The TLC and HPLC methods were adopted.RESULTS Cortex Phellodendri,Herba Desmodii Styracifolii and Rhizoma Alismatis were identified by TLC.The content of berberine hydrochloride in Niaoyanqing tablet was determined by HPLC.berberine hydrochloride showed a good linear relationship in the range of 39.28-78.56 μg(r=0.9999).The average recovery rate was 98.3% with RSD of 1.87%(n=6).CONCLUSION The established methods are simple,accurate,reliable and can be used for the quality control of Niaoyanqing tablet.
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OBJECTIVE To identify and determine of berberine hydrochloride of Niaoyanqing tablet.METHODS The TLC and HPLC methods were adopted.RESULTS Cortex Phellodendri,Herba Desmodii Styracifolii and Rhizoma Alismatis were identified by TLC.The content of berberine hydrochloride in Niaoyanqing tablet was determined by HPLC.berberine hydrochloride showed a good linear relationship in the range of 39.28-78.56 μg(r=0.9999).The average recovery rate was 98.3% with RSD of 1.87%(n=6).CONCLUSION The established methods are simple,accurate,reliable and can be used for the quality control of Niaoyanqing tablet.
Key concepts: Berberine hydrochloride, Chemistry, Chromatography, Berberine, High-performance liquid chromatography, Linear relationship, Hydrochloride, Content determination