Serum uric acid levels of hypertension patients in plateau area

Objective To discuss the relationship between hypertension and blood uric acid of patients in plateau area.Methods We chose 134 cases of hypertension patients from Tibet treated in our hospital from January 2007 to January 2010 as observation group,and 113 controls who took physical examinations in our hospital at the same time.All the subjects were fasting for 12 hours or more.About 2~3 ml venous blood was taken for inspection.Results Total and 3 levels of blood uric acid in observation group were significantly higher than those in control group(P0.001,P0.05,P0.05,P0.05).Blood uric acid of hypertensive patients in level 1 was significantly lower than that of hypertensive patients in level 2 and 3(P0.001,P0.05).There was no significant difference in blood uric acid between level 2 and 3 hypertensive patients(P0.05).Blood uric acid of male was significantly higher than that of female in both observation group and control group(P0.05,P0.001).Blood uric acid of Han people was significantly higher than that of Tibetan(P0.05).Conclusions The increase of blood uric acid is one of the causes of hypertension,and also one of the results from metabolism in hypertensive patients.The main causes are the increased production of blood uric acid and the decreased discharge of it.Blood uric acid of male is higher than that of female,and blood uric acid of Han people is higher than that of Tibetan.It is suggested to improve the lifestyle and eating habits.Balanced and lasting antihypertensive therapy is beneficial for improving metabolism and reducing blood uric acid level.