Clinical Study of the Incidence of Radioactive Pneumonia in Breast Cancer Postoperative Chemotherapy and Radiotherapy

Objective To discuss the effect of postoperative chemotherapy and radiotherapy to the incidence of radioactive pneumonia in breast cancer.Methods All 126 cases of postoperative breast cancer patients were divided into study group and control group,63 cases respectively.The study group was given CAF chemotherapy 6 cycles continuously and radiotherapy from armpit field by stages after stitches removed.The total dose was 50Gy.After 4 weeks,the radiotherapy from chest field was given as above.The control group was given CAF chemotherapy 2 cycles continuously and radiotherapy from armpit and chest field under routine schedule,50Gy total dose.Four more chemotherapy was given at intervals of 4 weeks.Results The incidence of radioactive pneumonia in study group was 7.9%,while in control group was 20.6%.The difference was significant(P0.05).The 5year survival rate in the study group was 68.1%,while in the control group was 69.8%.The difference was insignificant(P0.05).There was no significant difference about the incidence of the recurrence and remote metastatic between the two groups.The arrest of bone marrow in both groups was that WBC decreased by 1-3 grade,so therapy was not interrupted.Conclusion The incidence of radioactive pneumonia in breast cancer postoperative chemotherapy can be decreased greatly by radiotherapy by trains,while the local recurrence rate is not elevated.