Changes in coagulation function in patients with hepatocellular carcinoma and its clinical significance

Objective To evaluate the liver cancer when the prothrombin time(PT),activated partial thromboplastin time (APTT),thrombin time(TT),fibrinogen(FIB) and the clinical significance of the changes.Methods 66 cases of liver cancer patients and 58 healthy persons were detected in plasma coagulation and the observation of four coagulation function and liver function Child-Pugh classification of the relationship between the observed 30 cases of surgical patients with the same manner as the volume of blood loss during surgery and plasma after a three-day changes in drainage pipes.Results The liver lead to changes in blood coagulation mechanism of liver function with lower grade PT,APTT,TT gradually extended,FIB decreased in three of the PT,APTT,TT,FIB significant differences were liver function of patients with lower grade,after three days of bleeding volume and the plasma tube drainage are also increasing.Conclusion Detection of four indicators of coagulation can promptly and accurately reflect the liver damage in patients with liver function and coagulation.