Multislice CT brain perfusion imaging: improved techniques and early clinic experiences

Objective To explore the improved techniques of MSCT brain perfusion imaging and its clinical value. Methods Using self control study method,two healthy hybrid dogs were underwent routine and reformation 4-slice CT brain perfusion imaging.The delayed time and scanning time of routine and improved technique were 5s,50s and 8s,40s respectively. Six of 14 patients with acute ischemic stroke were underwent improved brain CT perfusion, and two also brain CT angiography. The mapping and value of cerebral blood flow (BF), cerebral blood volume (BV) and mean transit time (MTT) of ROI were analyzed and computed at workstation related the parameters of cerebral h ino-dynamics. T-test was used in statistical analysis. Results Diagnostic sources data were successfully acquired in all improved CTP scanrings. The mapping of BF、BV and MTT of internal capsule(posterior limb), lentiform nucleus and gray matter (superior temporal gyrus) in dog was similar in both usual and improved CTP. The mean value of BF、BV and MTT in these areas had no significant difference(p0.05) in the two CTP methods,and the exposure time of CT tube was decreased 10 seconds every CTP scan in the improved technique.The improved CT brain perfusion imagings accurately detected the site, region and degree of the acute cerebral ischemic nidi in all 6 cases. Conclusion The improved MSCT perfusion imaging has similar diagnostic effects with that of usual CTP, and the radiation-induced injuring will he deereas(?) as well as the tube lifetime will be prolonged.