Study of Hemostatic Effect of Chitosanbased Fibre
Gao Jin-wei
Abstract
Gao Jin-wei
Abstract
[Objective] The aim was to discuss the hemostatic effects of chitosanbased fibre for liver.[Method] The hemorrhage model of rabbit liver was established.Hemostasis was performed with chitosan-based fibre in experimental group,surgicel in control group and without any material in blank group.The hemostatic effects were evaluated by total blood loss(TBL) and hemostatic rate.[Result]Experimental group had no bleeding in observation period,the hemostatic rate was 100% and the blood loss was only(0.443±0.030)g/kg,better than the control group and blank group(P0.05).[Conclusion]Chitosanbased fibre has effective hemostasis in liver wound,which will provide reliable information for the clinical trials.
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[Objective] The aim was to discuss the hemostatic effects of chitosanbased fibre for liver.[Method] The hemorrhage model of rabbit liver was established.Hemostasis was performed with chitosan-based fibre in experimental group,surgicel in control group and without any material in blank group.The hemostatic effects were evaluated by total blood loss(TBL) and hemostatic rate.[Result]Experimental group had no bleeding in observation period,the hemostatic rate was 100% and the blood loss was only(0.443±0.030)g/kg,better than the control group and blank group(P0.05).[Conclusion]Chitosanbased fibre has effective hemostasis in liver wound,which will provide reliable information for the clinical trials.
Key concepts: Hemostasis, Hemostatic Agent, Medicine, Blood loss, Liver tissue, Surgery, Internal medicine