Relation of endoscopic biopsy channel disinfection with electrolyzed oxidizing water before ERCP cannulation with post-operative infection.

Objective To evaluate the relation of endoscopic biopsy channel disinfection with electrolyzed oxidizing water(EOW) before ERCP cannulation and postoperative infection. Methods Data were collected from 58 patients who had undergone therapeutic ERCP during March 2010 and July 2010 in Gastro-enterologic Endoscopy Center of the Beijing Friendship Hospital.Patients were divided randomly into EOW disinfection group(n=29) and Control group(n=29).In EOW disinfection group,the endoscopic biopsy channel and area around the papilla were rinsed with 20 mL EOW twice before cannulation.Specimens were obtained from endoscopic biopsy channel by rinsing with 10 mL of saline immediately after being used for bacterial culture. Results All the 58 patients were successfully operated in one performance.Compared with the control group,EOW group had a lower incidence of fever after operation(6.9% vs 27.6%,P0.05).None of the patients in EOW group and two in control group had suppurative cholangitis.Nineteen specimens were bacteria positive in EOW group,and all 29 specimens from the control group were bacteria positive(19/29 vs 29/29,P0.01). Conclusion Endoscopic biopsy channel disinfection with EOW before ERCP cannulation is effective in reducing postoperative infection.