Study on the prognostic factors of breast cancer after modified radical mastectomy and chemotherapy

Objective To explore the factors related to the prognosis of breast cancer after modified radical mastectomy and chemotherapy,to establish a prognostic model for evaluating the prognosis of their patients. Methods 96 cases with breast cancer after modified radical mastectomy and chemotherapy were selected in this study and the factors related to the prognosis were collected and followed. Cox regression analysis was used for univariate and multivariate analysis. Prognostic index(PI) was calculated based on the results of multivariate analysis. Results Univariate and multivariate analysis of Cox regression model were the tumor size,histopathological type and number of axillary metastasis lymph nodes. A prognostic model was established. Breast cancer after modified radical mastectomy and chemotherapy had a better three-year outcome with PI≤5. 23 by ROC curves. Conclusions Histopathological type and number of axillary metastasis lymph nodes seem to be independent and important prognostic factors. This prognostic model could be used to evaluate the prognosis of patients with breast cancer after modified radical mastectomy and chemotherapy by clinicians.