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The effects of Sodium Ferulate on diabetic nephropathy

Tang Shan-sha

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Abstract

Objective To investigate the effects of Sodium Ferulate(YiMiLe) on diabetic nephropathy. Methods 60 cases of type 2 diabetic nephropathy with microalbuminuria were randomly divided into two group:routine treatment group and YiMiLe group. Results Results showed that the elevated urinary albumin excretion rate (UAER) and urinary endothelin (ET) were markedly decreased and the disorder of lipid metabolism was significantly improved in YiMiLe group. These parameters except triglyceride (TG) had no significant change throughout the study in routine treatment group. Conclusion This study suggested that YiMiLe could improve diabetic nephropathy by antagonisting the combination of ET and its receptors and might have some protective effects as well. YiMiLe had good effects on lipid metabolism.

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What this paper is about

Objective To investigate the effects of Sodium Ferulate(YiMiLe) on diabetic nephropathy. Methods 60 cases of type 2 diabetic nephropathy with microalbuminuria were randomly divided into two group:routine treatment group and YiMiLe group. Results Results showed that the elevated urinary albumin excretion rate (UAER) and urinary endothelin (ET) were markedly decreased and the disorder of lipid metabolism was significantly improved in YiMiLe group. These parameters except triglyceride (TG) had no significant change throughout the study in routine treatment group. Conclusion This study suggested that YiMiLe could improve diabetic nephropathy by antagonisting the combination of ET and its receptors and might have some protective effects as well. YiMiLe had good effects on lipid metabolism.

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Available abstract

Objective To investigate the effects of Sodium Ferulate(YiMiLe) on diabetic nephropathy. Methods 60 cases of type 2 diabetic nephropathy with microalbuminuria were randomly divided into two group:routine treatment group and YiMiLe group. Results Results showed that the elevated urinary albumin excretion rate (UAER) and urinary endothelin (ET) were markedly decreased and the disorder of lipid metabolism was significantly improved in YiMiLe group. These parameters except triglyceride (TG) had no significant change throughout the study in routine treatment group. Conclusion This study suggested that YiMiLe could improve diabetic nephropathy by antagonisting the combination of ET and its receptors and might have some protective effects as well. YiMiLe had good effects on lipid metabolism.

Key concepts: Diabetic nephropathy, Microalbuminuria, Endocrinology, Internal medicine, Medicine, Nephropathy, Lipid metabolism, Endothelin receptor

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