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Genetic analysis of 35 microsatellite loci in three miniature pig breeds

Haitao Shang, Rong Niu, Hong Kui WEI, Huang Zhongbo, Shixiang Gan, Aide Wang, Yangzhi Zeng

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Abstract

The polymorphism of 35 mcrosatellites in the three miniature pig breeds in China (Guizhou miniature pig, Guangxi Bama miniature pig, Banna miniature pig inbred) was analysed. Rates of homozygote for 35 microsatellite loci in three miniature pig breeds were calculated, and t-test for them were performed. Mean heterozygosity and polymorphism information content (PIC) were calculated for all breeds, and genetic distances between these breeds were estimated. The dendrograms were obtained based on genetic distances. The results suggest that rates of homozygote in the three breeds are all high, and that is the highest in Banna miniature pig inbred. The results also suggest that polymorphism information content and mean heterozygosity in all the three breeds are low, and the genetic relationship between Guizhou miniature pig and Guangxi Bama miniature pig is closer than their relationship with Banna miniature pig inbred.

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What this paper is about

The polymorphism of 35 mcrosatellites in the three miniature pig breeds in China (Guizhou miniature pig, Guangxi Bama miniature pig, Banna miniature pig inbred) was analysed. Rates of homozygote for 35 microsatellite loci in three miniature pig breeds were calculated, and t-test for them were performed. Mean heterozygosity and polymorphism information content (PIC) were calculated for all breeds, and genetic distances between these breeds were estimated. The dendrograms were obtained based on genetic distances. The results suggest that rates of homozygote in the three breeds are all high, and that is the highest in Banna miniature pig inbred. The results also suggest that polymorphism information content and mean heterozygosity in all the three breeds are low, and the genetic relationship between Guizhou miniature pig and Guangxi Bama miniature pig is closer than their relationship with Banna miniature pig inbred.

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Available abstract

The polymorphism of 35 mcrosatellites in the three miniature pig breeds in China (Guizhou miniature pig, Guangxi Bama miniature pig, Banna miniature pig inbred) was analysed. Rates of homozygote for 35 microsatellite loci in three miniature pig breeds were calculated, and t-test for them were performed. Mean heterozygosity and polymorphism information content (PIC) were calculated for all breeds, and genetic distances between these breeds were estimated. The dendrograms were obtained based on genetic distances. The results suggest that rates of homozygote in the three breeds are all high, and that is the highest in Banna miniature pig inbred. The results also suggest that polymorphism information content and mean heterozygosity in all the three breeds are low, and the genetic relationship between Guizhou miniature pig and Guangxi Bama miniature pig is closer than their relationship with Banna miniature pig inbred.

Key concepts: Miniature pig, Biology, Loss of heterozygosity, Bama, Microsatellite, Inbred strain, Genetics, Polymorphism (computer science)

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