A Clinical Investigation on Early Application of rhG-CSF after Chemotherapy

Objective To investigate the effect of recombined human granulocyte colony-stimulating factor (rhG-CSF) on leukopenia and neutropenia induced by chemotherapy.Methods rhG-CSF began to be used within 24～48 hours after chemotherapy in treatment group,and in control group,rhG-CSF application was started when the blood granulocyte count being low.Results The absolute neutrophil count dropping time was shorter in the treatment group than that in the control group,and the infection rate decreased significantly in the former group.Conclusion This study showed that early treatment with rhG-CSF can decrease the absolute neutrophil count dropping time and infection rate.