2009•Journal of Bengbu Medical CollegeRequires access

CT perfusion imaging in preoperative grading of astrocytoma

Sun Jing-qiu

Abstract

Objective:To evaluate the role of CT perfusion imaging(CTP) in preoperative grading of astrocytoma.Methods:CTP was performed in 31 patients with astrocytioma.Forteen cases were proved to be low-grade astrocytoma and 17 cases high-grade astrocytoma.All the cases received CT and CTP examinations.The cerebral blood flow(CBF),cerebral blood volume(CBV) and permeability surface(PS) values were calculated,and the perfusion maps were statistically analyzed.Results:The CBF,CBV and PS value of the astrocytoma were higher than that of the normal brain tissue(P0.01).The CBF,CBV and PS value of high grade astrocytoma were higher than that of low grade astrocytoma(P0.01).There was a positive correlation among the CBF,CBV and PS value in the astrocytoma(P0.01).Conclusions:CTP has great clinical value in preoperative grading of astrocytoma.

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Key concepts: Medicine, Astrocytoma, Grading (engineering), Cerebral blood flow, Perfusion, Perfusion scanning, Cerebral blood volume, Nuclear medicine