Clinical Observation on the Effect of Patient Postoperative Controlled Epidural Analgesia with three Different Doses of Sufentanil

Objectives To evaluate the effect of patient postoperative-controlled epidural analgesia(PCEA)with different doses of sufentanil combined with 0.2% ropivacaine after hysterectomy.Methods Sixty patients(ASA Ⅰ～Ⅱ)underwent elective hysterectomy were randomly divided into three groups.Group A was given sufentanil 0.3 μg/ml+0.2% ropivacaine for PCEA,group B was given sufentanil 0.4 μg/ml +0.2% ropivacaine for PCEA,group C was given sufentanil 0.5 μg/ml+0.2% ropivacaine for PCEA.The PCEA device was programmed loading dose 5 ml,bolus of 1 ml with lock time 20 minutes and background 4 ml/h.The analgesia effects were evaluated by the number of PCA demand、visual analogue scales、 bruggrmann comfort scale and bromage score.Side effects such as nausea and vomiting were also recorded.Results The VAS scores were significantly higher in group A than that in group B and group C(P0.05),the differences of VAS were not significant between group B and group C(P0.05).The incidence of nausea was related to the dose of sufentanil used and it was significantly higher in group C than that in group A and group B(P0.05).The patients of three groups were uneventful.Conclusion 0.4 μg/ml sufentanil+0.2% ropivacaine is recommended for PCEA with background 4 ml/h was safe and effective for patient after hysterectomy.