Study on serotype distribution in 48 isolates of invasive Streptococcus pneumoniae with which children infected

Purpose To investigate serotype distribution of invasive Streptococcus pneumoniae of clinical isolates in Nanjin.Methods A total of 48 strains invasive Streptococcus pneumoniae were collected from January 2007 to December 2010.Serotyping of Streptococcus pneumoniae was performed by using quelling reaction.Results The most common serotypes 48 Streptococcus pneumoniae isolates were 19F(27.1%)、19A(22.8%)、14(18.7%)and 9v(8.3%).There were two strains(4.2%)that cannot be identified with the antisera used.Conclusion The major serotypes of invasive Streptococcus pneumoniae with which children infected in Nanjing are 19F,19A,14 and 9v.