Study on Dobutamine Stress Strain Imaging for the Diagnosis of Senile Coronary Artery Disease

Objective To explore the clinical value of dobutamine stress echocardiography(DSE)and stress imaging(SI)in the diagnosis of senile coronary artery disease(CAD).Methods 98 cases of suspended CAD were underwent DSE+SI.Peak strain(Speak)of mid-segment systolic period of various ventricular walls was detected.The complete coronary angiography(CAG)was performed in 2 weeks.According to the results of CAG,a CAD group and a normal group were divided.Results Speak at each myocardial segment during dobutamine stress by 10 and 20 μg·kg-1·min-1 was less than that in normal group,indicating statistical significant difference(P0.05或P0.01).However Speak during dobutamine stress in 40 μg·kg-1·min-1 did not present significant difference between two groups(P0.05).As compared with CAG,the sensitivity,specificity and accuracy of Speak in the diagnosis of senile CAD were 78.6%,72.3% and 74.7% separately.The sensitivity and specificity at each dobutamine dose were various.They were up to the highest,85.4% and 67.4% separately at 20 μg·kg-1·min-1 stress.The topical diagnosis of three coronary vessels presented high specificity.The incidence of adverse reaction was low.Conclusion Dobutamine stress quantitative strain imaging is a safe,effective and non-invasive technique for the diagnosis of senile CAD.