On the Electrochemical Oxidation of Tyrothricine Glassy Carbon Electrodes

The electrochemical oxidation of tyrothricine at glassy carbon electrodes has been studied in aqueous solutions over a wide PH range. The mechanism for the oxidation of tyrothricine was studied by several modern electrochemical techniques including linear sweep voltammetry, cyclic voltammetry, square wave voltammetry and chronocoulometry, and combining with UV spectroscopy. Our studies revealed that the electrochemical oxidation of tyrothricine at glassy electrodes was an overall chemically irreversible process involving the same number of electrons and protons transferrng. Tyrothricine itself did not adsorb at glassy carbon electrodes, however, the electrooxidation product with no electrochemical activity can strongly adsorb at the electrodes, which resulted in deactivation of the electrode surface. The response of tyrothricine was found to be the most sensitive at PH2.0 with square wave voltammetry, and the detection limit was 8.3×10\+\{-7\}mol/L.