CO_2 laser in treatment of T_1 well-differentiated squamous cell carcinoma in the glottic portion involving the anterior commissure under microscopy

Objective To evaluate the oncologic safety of microscopic CO2 laser in treatment of stage T1 well-differentiated squamous cell carcinoma in the glottic portion involving the anterior commissure.Method The clinical data of 56 cases from March 2005 to June 2007 were retrospectively analyzed.Results 11 cases (19.6%) locally recurred,of them,4 cases(4/37) were unilateral cord lesion,5(5/13) were cord and anterior commissure lesion,and 2(2/6) were horseshoes lesion involving both the cords and the anterior commissure.The recurrent rate of cases of cord and anterior commissure lesion and horseshoes lesion was higher than that of unilateral cord lesion.Followed up for an average of 26.4 months(10-32 months),the preservation rate of the laryngeal function was 96.4%.Conclusion Microscopic CO2 laser for glottic carcinoma is limited to some extent,and it should be carefully used in carcinoma involving the anterior commissure.