Evaluation of Fuji Intelligent Chromo Endoscopy in the diagnosis of colorectal neoplasia

Objective To investigate the value of Fuji Intelligent Chromo Endoscopy (FICE) for the diagnosis of colorectal neoplasia. Methods Five hundred and fifty-one patients were examined with ordinary colonoscopy from Aug. 2007 to Mar. 2008. One hundred and ninety-seven patients with colonic neoplasia or polypoid lesions were enrolled in this study. The patients were examined with magnifying conventional colonoscopy, magnifying FICE technique and magnifying chromoendoscopy technique, the pit pattern and blood capillary form of the lesion were examined. The endoscopic diagnosis was made, and compared with pathological diagnosis. Results Three hundred and ninety-eight neoplasms were detected in 197 patients, among those 90.8%(361/398) were detected with magnifying endoscopy, 98.7%(393/398) were detected with FICE technique, there was significant difference between the two methods. The coincident rate of FICE for the diagnosis of tumor and non-tumor lesions was 90.2%(359/398), which was significant higher than that of chromoendoscopy 82.4%(328/398)(P = 0.001). Conclusions Magnifying FICE could show mucosal microstructure and blood capillary form. It had higher power in distinguishing neoplastic from non-neoplastic colorectal lesions compared with magnifying colonoscopy and magnifying chromoendoscopy.