valuation of Clinical Application of Detective System of Multi-tumor Markers Protein Chip for ovarian cancer

OBJECTIVE To evaluate the clinical applications to early diagnosis and monitoring prognosis with multi-tumor markers protein chip in ovarian cancer.METHODS The serum levels of tumor markers were measured with the detective system in 100 patients with ovarian cancer 100 healthy women as control.Random negative samples detected by multi-tumor markers protein chip were also measured by E601.RESULTS The sensitivity of tumor markers was 83% in patients with ovarian cancer.There were two positive samples among 100 healthy women(the specificity was 98%).The level of tumor markers decreased significantly in the first 3-4 weeks in 83 cases of C-12-positive patients with ovarian cancer after radical surgery.But there were no significant difference among 3 months,6 months,and 12 months.CONCLUSION Multiple tumor marker protein chip detection system could significantly improve the sensitivity and specificity for the diagnosis of ovarian cancer,and monitor the prognosis and therapeutic response,which is of important clinical significance.