Clinical analysis of systemic inflammatory response syndrome and multiple organ dysfunction syndrome in children infectious disease

Objective To investigate the opportunity of systemic inflammatory response syndrome(SIRS) and the risk factors of multiple organ dysfunction syndrome(MODS) in children infectious disease.Methods According to the criteria of SIRS and MODS,938 cases who was hospitalized owing to pure infectious disease were studied for the morbidity of SIRS and MODS.Results 125 cases(13 3%) were diagnosed as SIRS.Whether single or multiple organ dysfunction,the occurrence rate was higher in SIRS group than that of non SIRS group( P 0 01).The risk factors of MODS related to the four criteria of SIRS,the more cases met the criteria,the more MODS happened..Conclusion The SIRS patients have high incidence of MODS and the incidence tend to be in proportion to the number meeting of four SIRS′ criteria.We recommend that early intervention should be taken in SIRS cases,in order to avoid MODS′ developing.