2006•Heilongjiang yiyao kexueRequires access
Correlation analysis of E_cadherin expression in oral squamous cell carcinoma and lymph node metastasis
Chi Hong-yu
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Abstract
Objective:To investigate the correlation between the expression of adhesion molecule E_cadherin in oral squamous cell carcinoma and lymph node metastasis.Method: The E_cadherin expression in 40 cases of oral squamous cell carcinoma was investigated by using immunohistochemical staining.Result: There was difference between the E_cadherin expression in the normal oral mucous epithelia and oral squmous cell carcinoma.The staining degree was significantly correlated with lymph node metastasis. Conclusion: The E_cadherin expression in oral squamous cell carcinoma with lymph node metastasis was much lower than that without metastasis,and therefore,the E_cadherin expression may be used as a marker of prognosis.