Experimental observation in repairing articular cartilage defects with transplanting complex tissue of red bone marrow and periosteum

OBJECTIVETo experimentally study the process of morphological changes in repairing articular cartilage defects with transplanting complex tissue of red bone marrow and periosteum.?METHODS?Using 24 Chinese rabbits, the 3 0?mm×6 0?mm of articular cartilage defects were produced on the knee joint by surgery and it was randomly divided group A that was transplanted with complex tissue of red bone marrow and periosteum and group B with periosteum only. The morphological changes of repaired tissue in the different session were observed and measured by macroscopy, light and electronic microscopy and technology of image analysis. ?RESULTS?The morphology, distribution and arrangement of repaired tissues and cells were reached to the normal cartilage tissue in group A and the area of single repaired cell was reached the normal chondrocyte in group B after 8th and 12th weeks of operation, respectively.?CONCLUSION?The transplantation of complex tissue of red bone marrow and periosteum could repair the articular cartilage defects and the repairing time in transplanting complex tissue of red bone marrow and periosteum is shorter than that in transplanting the periosteum only.