Dual-source CT perfusion imaging in hepatocellular carcinoma

Objective To investigate the dual-source CT perfusion imaging(CTPI) features of hepatocellular carcinoma(HCC) and its clinical value.Methods CT perfusion scans were performed with dual-source CT in 30 HCC patients.Arterial liver perfusion(ALP),portal venous perfusion(PVP),hepatic perfusion index(HPI),blood flow(BF),perseability(P) and patlak blood volume(pBV) of all HCC lesions were collected and analyzed by body PCT perfusion software build dual-source CT.Results (1) Time-density curve(TDC) of HCC raised and peaked quickly in arterial phase and then the curve stayed unchanged for a time or descended quickly.(2)The tumor tissue demonstrated hyper-perfusion on ALP,HPI,BF,P and pBV map in all cases,of which homogeneous hyper-perfusion was showed in 10 cases and inhomogeneous hyper-perfusion in 20 cases and no blood perfusion in the necrosis tissue.(3)The values of ALP,HPI,BF,pBV were higher,but PVP was lower,in the tumor than those in the tumor-adjacent tissues and the normal liver(P0.05).(4)The values of ALP,BF of the liver tissue around the lesion with a blurring edge were higher than those of the lesions with a clear edge(P0.05).(5)The size of HCC lesions measured on CTPI was larger than that on original CT images.Conclusion Dual-source CTPI can provide much more information about the hemodynamics features of HCC,which is helpful in diagnosing and treating the diseases.