2003•Dalian Yike Daxue xuebaoRequires access

Telomerase catalytic subunit and tumor

Zhenlan Song

Abstract

Human telomerase catalytic subunit (e.g. human telomerase reverse transcriptase, hTERT)which is rate-limiting enzyme of telomerase, is consistent with expression of telomerase activity and specific for tumor?Some chemotherapic remedy, Chinese medicine, ribozyme and antisense oligos can inhibit expression of hTERT-mRNA and telomerase activity , slow the growth of tumor.

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Available abstract

Key concepts: Telomerase, Telomerase reverse transcriptase, Protein subunit, Reverse transcriptase, Ribozyme, Molecular biology, Telomere, Messenger RNA