Survival Analysis on 59 Cases with Nephroblastoma

To study the present survival status of nephroblastoma(Wilms'tumor,WT) and the relationship between pathologic classification,clinicopathologic stage and WT.A total of 59 patients between Jan. 1996 and Dec.2002 with WT were analyzed retrospectively,with stageⅠ,21 cases;stageⅡ,14 cases;stage Ⅲ,16 cases;stage Ⅳ,5 cases;stage Ⅴ,3 cases according to NWTS-5 clinicopathologic staging. There are 7 cases (13.2%) with unfavorable histology (UH) type and 46 cases (86.8%) with favorable histology (FH) type among 53 patients treated with tumorectomy.Kaplan-Meier method was used to analyzed survival.Fifty-one patients have been followed up with follow-up rate 86.4%(51/59).Among these 51 cases, 14(24.5%) cases died, 37(72.5%) cases were still alive.1-,2-,and 5-year survival rates were 87.0%?80.0%和70.0% respectively.2-,5-year survival rates in FH type were higher than those in UH type (P=0.008).Declining trend in survival rate with the increasing of clinicopathologic stage was found.[Conclusion]The 5-year survival rate is 70.0% in this group according to Kaplan-Meier analysis.Pathologic classification and clinicopathologic stage have influence on survival of WT.