Pathogen of hand,foot and mouth disease in children in pingdingshan in 2009

Objective:Scientific proof of HFMD prevention and cure is provided by knowing the etiologic features of HFMD in Pingdingshan in 2009.Methods: Tests are done with RT-PCR by collecting 764 specimens from 468 HFMD children's feces serum,nasopharyngeal swab,fluid from blisters,and CSF.Results: 318 children are tested positive for enterovirus from 468 with rate is 67.95%,among of that EV71 infections rate is the highest which is 37.18%.452 out of 764 specimens are tested positive for enterovirus with rate of 59.16%,in which stool specimen tested positive is 67.65%.Severe children tested positive for enterovirus is 76.39% and of which 116 are tested EV71 infection which accounts for 70.30%.The HFMD happens more in male than that in female by ratio of 1.75∶1.Male tested positive for enterovirus is higher than that in female.93.36% tested positive for enterovirus are children below age 4.Conclusion: EV71 pathogen serves to be the main source in children HFMD and feces specimens test PCR positive appears high in children in Pingdingshan in 2009.