Synthesis of 3-Phenyl-pyrrolo[2,1,5-cd]indolizine-1-carboxylic acid(2-hydroxy-benzylidene)-hydrazide and Its Application as Fluorescent Sensors for Cu~(2+)

3-Phenyl-pyrrolo[2,1,5-cd]indolizine-1-carboxylic acid(2-hydroxy-benzylidene)-hydrazide(6) was synthesized and used as fluorescent sensors for Cu2+ ion.The structure of the compound 6 was determined by IR,1H NMR,MS and elemental analysis and their UV and fluorescence spectra were measured.The influences of ten metal ions such as Cu2+,Zn2+,Ni2+,Co2+,Al3+,Cr3+,Mn2+,Na+,Sn2+ and Ca2+ on their fluorescence properties were studied.Spectroscopic studies revealed that the compound 6 had rather strong affinity toward Cu2+.The specificity of the probe 6 toward Cu2+ was determined.Nearly no fluorescence intensity changes were observed in emission spectra with Zn2+,Ca2+,Na+,K+,Cr3+,Sn2+,Al3+ but Ni2+ and Co2+.However,under identical conditions,the results showed fluorescence quenching with Cu2+.So we have developed a new fluorescent sensor 6.It shows high sensitivity and selectivity toward Cu2+ in DMSO.