2012•The Journal of Pharmaceutical PracticeRequires access
Progress in pulsatile drug delivery system
Xu Pan
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Abstract
Pulsatile drug delivery system developed quickly with the further study of chronobiology and chronopharmacology,which controled drug release and dosage by the method of formulation,and could coordinate the change of physiological rhythm,furthermore ensure efficacy and reduce adverse reaction.The characteristics and drug release mechanism of pulsatile drug delivery system were introduced and the clinical applications of pulsatile drug delivery system in recent years were discussed.