Effects of Cranial Sutures Acupuncture Plus Drugs on Recovery of Neural Function and Serum SOD and MDA in Acute Cerebral Infarction Patients with Phlegm Syndrome

Objective To explore the effects of cranial sutures acupuncture plus drugs on recovery of neural function and serum superoxide dismutase(SOD) and malonaldehyde(MDA) in acute cerebral infarction(ACI) patients with phlegm syndrome.Methods 40 ACI patients with phlegm syndrome were randomly divided into two groups,the control group(group A,n=20) was treated with routine drugs and the treatment group(group B,n=20) with routine drugs and acupuncturing at cranial sutures.The score of neurologic impairment,score of TCM syndromes and the changes of content of serum SOD and activity of MDA were observed.Results Compared with the normal range,the activity of serum SOD in ACI patients with phlegm syndrome were decreased significantly and the content of MDA were increased significantly.The scores of neurologic impairment and scores of TCM syndromes were decreased significantly,the activity of serum SOD was increased significantly,and the content of serum MDA was decreased significantly after treatment in both groups.The change amplitude in group B was higher than that in group A,and there were significant difference between them.Conclusion Cranial sutures acupuncture plus drugs can improve neural function of ACI patients,alleviate clinical symptoms.Its mechanism is probably related with the effects of increasing SOD activity,reducing MDA content and alleviating reperfusion injury.