Evaluation effects of CHA2DS2-VASc scale on risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction

Objective To explore the evaluation effects of CHA2DS2-VASc scale on risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction.Methods Two hundred and eight patients were evaluated by CHADS2 scale and CHA2DS2-VASc scale.The occurrences of cerebral infarction within one year followed up were observed.Results The area under the receiver operative characteristic(AUCROC) of CHADS2 and CHA2DS2-VASc were 0.66 and 0.74 in predicting the risk of cerebral infarction within one year.According to CHA2DS2-VASc criteria,There was no secondary cerebral infarction in low risk group;just one patient(3.6%) had secondary cerebral infarction in medium risk group;while 23 patients(13.5%) had secondary cerebral infarction in high risk group.There were statistical differences in the incidence of cerebral infarction among three groups(all P 0.05).The linear regression analysis showed that CHA2DS2-VASc score was positive correlation with the occurrence of cerebral infarction in nonvalvular atrial fibrillation patients(r = 0.373,P = 0.001).According to CHA2DS2-VASc criteria,the incidence of cerebral infarction was no statistical difference between different sex patients(P 0.05),while other score items had statistical differences(all P 0.05).Conclusion CHA2DS2-VASc scale can effectively predict the risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction.