Clinical observation to different locations of AMI and hs-CRP and Hcy in plasma

Objective To explore the relationship between the different locations of acute myocardial infarction with elevated ST segment(STEMI) as well as coronary narrowing and the levels of high-sensitive C-reactive protein(hs-CRP) and hemoeysteine(Hcy) in plasma.Methods Sixty-nine patients of STMI were divided into group-1(n=37, the infarction was located in the wide anterior wall) and group-2(n=32, the infarction was located in the inferior wall) by ECG and coronary angiogram. The hs-CRP and Hcy in plasma were tested for all of the patients with venous blood samples taken within 24 hours of the AMI.Results The hs-CRP and Hcy was elevated over the normal level significantly in both of the two groups(P0.05). That was higher in group-1 than that of group-2 but the difference was not significant(P0.05).Conclusion Both hs-CRP and Hcy are risk factors of AMI and may reflect the extent of the myocardial injury and coronary narrowing.